Invention Grant
- Patent Title: Hydrophobic modified peptides for liver specific diagnosis
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Application No.: US13984715Application Date: 2012-02-10
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Publication No.: US10363323B2Publication Date: 2019-07-30
- Inventor: Walter Mier , Stephan Urban , Stefan Mehrle , Uwe Haberkorn , Thomas Müller , Vasileios Askoxylakis
- Applicant: Walter Mier , Stephan Urban , Stefan Mehrle , Uwe Haberkorn , Thomas Müller , Vasileios Askoxylakis
- Applicant Address: DE Heidelberg
- Assignee: RUPRECHT-KARLS-UNIVERSITAT HEIDELBERG
- Current Assignee: RUPRECHT-KARLS-UNIVERSITAT HEIDELBERG
- Current Assignee Address: DE Heidelberg
- Agency: Barnes & Thornburg LLP
- International Application: PCT/EP2012/052343 WO 20120210
- International Announcement: WO2012/107577 WO 20120816
- Main IPC: A61K51/08
- IPC: A61K51/08 ; A61K38/00 ; A61K49/00 ; A61K49/08 ; A61K49/14 ; C07K14/005 ; C12N7/00

Abstract:
The present invention relates to hydrophobic modified peptides for the specific delivery of labels to the liver, preferably to hepatocytes, in vitro as well as in vivo. The present invention relates to pharmaceutical compositions comprising said hydrophobic modified peptide(s) and the label(s) to be specifically delivered to the liver. The present invention furthermore relates to the diagnostic use of the inventive hydrophobic modified peptides as well as to a method for the diagnosis of liver diseases or disorders.
Public/Granted literature
- US20140356284A1 HYDROPHOBIC MODIFIED PEPTIDES FOR LIVER SPECIFIC DIAGNOSIS Public/Granted day:2014-12-04
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