A temperature control system of a mobile device is provided. The system includes a memory for storing a set temperature value and a release temperature value, a temperature sensor for sensing an internal temperature of the mobile device; at least one module that emits heat, and a controller. The controller compares the output of the temperature sensor with the set temperature value in a normal mode in order to determine whether the mobile device is overheated, and controls, if the mobile device is overheated, the at least one module to operate in a heat generation suppressing mode, compares the output of the temperature sensor with the release temperature value in the heat generation suppressing mode in order to determine whether to release the heat generation suppressing mode, and executes the normal mode if the heat generation suppressing mode is released according to the comparison result.