Invention Grant
- Patent Title: Process for preparing BTK inhibitors
-
Application No.: US15841828Application Date: 2017-12-14
-
Publication No.: US10385058B2Publication Date: 2019-08-20
- Inventor: Danial Beaudry , Theresa Cravillion , Francis Gosselin , Ngiap-Kie Lim , Sushant Malhotra , Qingping Tian , Haiming Zhang , Alexander Gmehling , Alec Fettes , Stephan Bachmann
- Applicant: Genentech, Inc.
- Applicant Address: US CA South San Francisco
- Assignee: Genentech, Inc.
- Current Assignee: Genentech, Inc.
- Current Assignee Address: US CA South San Francisco
- Agent Mark D. Kafka
- Main IPC: C07D487/04
- IPC: C07D487/04 ; B01J31/24
Abstract:
Methods for preparing the Bruton's Tyrosine Kinase (“BTK”) inhibitor compound 2-{3′-hydroxymethyl-1-methyl-5-[5-((S)-2-methyl-4-oxetan-3-yl-piperazin-1-yl)-pyridin-2-ylamino]-6-oxo-1,6-dihydro-[3,4′]bipyridinyl-2′-yl}-7,7-dimethyl-3,4,7,8-tetrahydro-2H,6H-cyclopenta[4,5]pyrrolo[1,2-a]pyrazin-1-one are provided. Methods for preparing tricyclic lactam compounds are also provided.
Public/Granted literature
- US20180230155A1 PROCESS FOR PREPARING BTK INHIBITORS Public/Granted day:2018-08-16
Information query
