Invention Grant
- Patent Title: Thionucleoside derivative or salt thereof, and pharmaceutical composition
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Application No.: US16037375Application Date: 2018-07-17
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Publication No.: US10385089B2Publication Date: 2019-08-20
- Inventor: Hidenobu Kuniyoshi , Daisuke Nakagawa , Takuya Matsumoto , Yuji Yoshimitsu
- Applicant: FUJIFILM Corporation
- Applicant Address: JP Tokyo
- Assignee: FUJIFILM Corporation
- Current Assignee: FUJIFILM Corporation
- Current Assignee Address: JP Tokyo
- Agency: Sughrue Mion, PLLC
- Priority: JP2014-222527 20141031
- Main IPC: C07H19/10
- IPC: C07H19/10 ; A61P35/02 ; A61K31/7068 ; A61P35/00

Abstract:
Disclosed are a compound and a pharmaceutical composition that exhibit an excellent drug efficacy against a tumor, in particular a tumor which has acquired resistance to gemcitabine. Specifically, provided is a thionucleoside derivative represented by General (in the formula, R1 represents a hydroxyl group which may be protected, a C1-20 alkoxy group which may be substituted, or the like; R2 represents a C1-20 alkoxy group which may be substituted, a C3-8 cycloalkoxy group which may be substituted, or the like; and R3 represents a hydrogen atom or the like); or a salt thereof. Further, provided is a pharmaceutical composition containing such a thionucleoside derivative or a salt thereof.
Public/Granted literature
- US20180319834A1 THIONUCLEOSIDE DERIVATIVE OR SALT THEREOF, AND PHARMACEUTICAL COMPOSITION Public/Granted day:2018-11-08
Information query
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