发明授权
- 专利标题: Mutant CsgG pores
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申请号: US15507947申请日: 2015-09-01
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公开(公告)号: US10400014B2公开(公告)日: 2019-09-03
- 发明人: Stefan Howorka , Han Remaut , Lakmal Jayasinghe , Elizabeth Jayne Wallace , James Anthony Clarke , Richard George Hambley , Jonathan Bankes Pugh
- 申请人: Oxford Nanopore Technologies Ltd. , VIB VZW , Vrije Universiteit Brussel
- 申请人地址: GB Oxford BE Ghent BE Brussels
- 专利权人: Oxford Nanopore Technologies Ltd.,VIB VZW,Vrije Universiteit Brussel
- 当前专利权人: Oxford Nanopore Technologies Ltd.,VIB VZW,Vrije Universiteit Brussel
- 当前专利权人地址: GB Oxford BE Ghent BE Brussels
- 代理机构: Wolf, Greenfield & Sacks, P.C.
- 优先权: GB1415455.3 20140901; GB1422079.2 20141211; GB1506489.2 20150416; GB1506754.9 20150421; GB1508287.8 20150514; GB1511203.0 20150625; GB1515240.8 20150827
- 国际申请: PCT/EP2015/069965 WO 20150901
- 国际公布: WO2016/034591 WO 20160310
- 主分类号: C12Q1/68
- IPC分类号: C12Q1/68 ; C07K14/245 ; C12Q1/6869 ; C12Q1/6874 ; G01N27/447
摘要:
The invention relates to mutant forms of the outer membrane-located lipoprotein CsgG, in particular, modifications at one or more of positions Tyr51; Asn55; and Phe56. The invention also relates to analyte detection and characterisation using said mutant CsgG.
公开/授权文献
- US20180148481A2 MUTANT CSGG PORES 公开/授权日:2018-05-31
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