Invention Grant
- Patent Title: Nanopore-based single DNA molecule characterization, identification and isolation using speed bumps
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Application No.: US15435206Application Date: 2017-02-16
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Publication No.: US10400278B2Publication Date: 2019-09-03
- Inventor: Randall W Davis , Roger J. A. Chen
- Applicant: Genia Technologies, Inc.
- Applicant Address: US CA Santa Clara
- Assignee: Genia Technologies, Inc.
- Current Assignee: Genia Technologies, Inc.
- Current Assignee Address: US CA Santa Clara
- Agency: FisherBroyles, LLP
- Agent Victoria L. Boyd
- Main IPC: C12Q1/6869
- IPC: C12Q1/6869 ; C12Q1/6816 ; G01N33/487 ; B82Y15/00 ; G01N27/447 ; C12Q1/6825 ; B82Y10/00
Abstract:
The present invention relates to a method of using nanopores to obtain sequence information of sample DNAs in ss test DNAs. The method comprises using speed bumps to stall the ss test DNAs in the nanopores at random positions of the ss test DNAs to obtain sequence information of each and every nucleotides of the sample DNAs, and to construct the whole sequences of the sample DNAs. The present invention also relates to identification and/or isolation of test DNAs having desired sequence(s) using nanopore detectors facilitated by speed bump.
Public/Granted literature
- US20170159117A1 Nanopore-Based Single DNA Molecule Characterization, Identification and Isolation Using Speed Bumps Public/Granted day:2017-06-08
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