Invention Grant
- Patent Title: Indolinyl-sulfonamide inhibitors of tankyrase and methods of use thereof
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Application No.: US15571240Application Date: 2016-05-02
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Publication No.: US10420758B2Publication Date: 2019-09-24
- Inventor: Lawrence Lum , Chuo Chen , Xuewu Zhang , Ozlem Kulak , Xiaofeng Wu
- Applicant: The Board of Regents of the University of Texas System
- Applicant Address: US TX Austin
- Assignee: The Board of Regents of the University of Texas System
- Current Assignee: The Board of Regents of the University of Texas System
- Current Assignee Address: US TX Austin
- Agency: Parker Highlander PLLC
- International Application: PCT/US2016/030364 WO 20160502
- International Announcement: WO2016/179066 WO 20161110
- Main IPC: A61K31/454
- IPC: A61K31/454 ; A61K45/06
Abstract:
The present disclosure provides compounds that may be useful for inhibiting the Tankyrase enzyme. In some aspects, these compounds are useful in the treatment of a disease or disorder related to the misregulation of Tankyrase enzyme such as cancer, degenerative diseases, or fibrotic diseases. Also provided herein are compounds may also be used to prevent the elongation of the telomere in a cell.
Public/Granted literature
- US20180271848A1 INDOLINYL-SULFONAMIDE INHIBITORS OF TANKYRASE AND METHODS OF USE THEREOF Public/Granted day:2018-09-27
Information query
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