- 专利标题： Factor VIII compositions and methods of making and using same
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申请号： US14379192申请日： 2012-07-11
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公开(公告)号： US10421798B2公开(公告)日： 2019-09-24
- 发明人: Volker Schellenberger , Pei-Yun Chang , Fatbardha Varfaj , Sheng Ding , Joshua Silverman , Chia-wei Wang , Benjamin Spink , Willem P. Stemmer , Nathan Geething , John Kulman , Tongyao Liu , Garabet G. Toby , Haiyan Jiang , Robert Peters , Deping Wang , Baisong Mei
- 申请人： Volker Schellenberger , Pei-Yun Chang , Fatbardha Varfaj , Sheng Ding , Joshua Silverman , Chia-wei Wang , Benjamin Spink , Willem P. Stemmer , Volker Schellenberger , Nathan Geething , John Kulman , Tongyao Liu , Garabet G. Toby , Haiyan Jiang , Robert Peters , Deping Wang , Baisong Mei
- 申请人地址： US MA Waltham
- 专利权人： BIOVERATIV THERAPEUTICS INC.
- 当前专利权人： BIOVERATIV THERAPEUTICS INC.
- 当前专利权人地址： US MA Waltham
- 代理机构： Lathrop Gage LLP
- 代理商 James H. Velema, Esq.
- 国际申请： PCT/US2012/046326 WO 20120711
- 国际公布： WO2013/122617 WO 20130822
- 主分类号： C07K14/755
- IPC分类号： C07K14/755 ; A61K38/00
摘要：
The present invention relates to compositions comprising factor VIII coagulation factors linked to extended recombinant polypeptide (XTEN), isolated nucleic acids encoding the compositions and vectors and host cells containing the same, and methods of making and using such compositions in treatment of factor VIII-related diseases, disorders, and conditions.
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