Invention Grant
- Patent Title: Engineered proteins with a protease cleavage site
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Application No.: US15600553Application Date: 2017-05-19
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Publication No.: US10421953B2Publication Date: 2019-09-24
- Inventor: William Jeremy Blake , Drew S. Cunningham
- Applicant: GreenLight Biosciences, Inc.
- Applicant Address: US MA Medford
- Assignee: GreenLight Biosciences, Inc.
- Current Assignee: GreenLight Biosciences, Inc.
- Current Assignee Address: US MA Medford
- Agency: Wolf, Greenfield & Sacks, P.C.
- Main IPC: C12N9/92
- IPC: C12N9/92 ; C12N9/10
Abstract:
Various aspects and embodiments herein relate to recombinant proteins with at least one protease recognition sequence, wherein the recombinant proteins can be inactivated by a cognate protease and methods of preparing such proteins. In some embodiments, recombinant phosphoglucose isomerase (Pgi) proteins are provided. In other embodiments, recombinant phosphotransacetylase (Pta) proteins are provided. In yet other embodiments, recombinant transketolase A (TktA) proteins are provided.
Public/Granted literature
- US20170253866A1 ENGINEERED PROTEINS WITH A PROTEASE CLEAVAGE SITE Public/Granted day:2017-09-07
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