A fuel cell stack, a method of operating a fuel cell stack and a fuel cell system. In one particular form, shutting down the stack upon detection of a leakage of fuel either within the stack or from the stack involves depressurizing and uniform consumption of hydrogen by catalytic consumption in the cathode of all cells. Upon consumption of oxygen in the cathode portion of the stack by chemical reaction, the remaining unreacted nitrogen from the air acts as an inerting fluid. After an indication of reaction cessation is established, at least some of the inerting fluid is conveyed from the cathode portion to the anode portion. One or more of a bleed valve, backpressure valve and bypass valve are manipulated to promote the anode portion depressurization, cathode portion inerting and subsequent conveyance of the inerting fluid to the stack anode portion.