Invention Grant
- Patent Title: Hepatitis B antiviral agents
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Application No.: US15088517Application Date: 2016-04-01
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Publication No.: US10442788B2Publication Date: 2019-10-15
- Inventor: Yao-Ling Qiu , Hui Cao , Wei Li , Jorden Kass , Xuri Gao , Xiaowen Peng , Meizhong Jin , Yat Sun Or
- Applicant: ENANTA PHARMACEUTICALS, INC.
- Applicant Address: US MA Watertown
- Assignee: Enanta Pharmaceuticals, Inc.
- Current Assignee: Enanta Pharmaceuticals, Inc.
- Current Assignee Address: US MA Watertown
- Agency: Elmore Patent Law Group, P.C.
- Agent Edgar W. Harlan; Carolyn S. Elmore
- Main IPC: C07D233/64
- IPC: C07D233/64 ; C07D401/12 ; C07F7/18 ; A61K31/4164 ; A61K31/454 ; A61K31/496 ; A61K31/5377 ; A61K31/55 ; A61K31/553 ; A61K31/695 ; A61K45/06 ; C07D401/14 ; C07D403/12 ; C07D409/14 ; C07D413/12 ; C07D413/14 ; C07D417/14 ; C07F9/6558 ; A61K31/4178 ; A61K31/661
Abstract:
The present invention discloses compounds of Formula (I), or pharmaceutically acceptable salts, esters, or prodrugs thereof: X-A-Y—Z-L-R1 (I) which inhibit the protein(s) encoded by hepatitis B virus (HBV) or interfere with the function of the HBV life cycle of the hepatitis B virus and are also useful as antiviral agents. The present invention further relates to pharmaceutical compositions comprising the aforementioned compounds for administration to a subject suffering from HBV infection. The invention also relates to methods of treating an HBV infection in a subject by administering a pharmaceutical composition comprising the compounds of the present invention.
Public/Granted literature
- US20160289212A1 HEPATITIS B ANTIVIRAL AGENTS Public/Granted day:2016-10-06
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