- 专利标题: Potent phthalate inhibitors of aspartate N-acetyltransferase and selective aspartate pathway inhibitors
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申请号: US15755447申请日: 2016-08-29
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公开(公告)号: US10449168B2公开(公告)日: 2019-10-22
- 发明人: Ronald E. Viola , Bharani Thangavelu , Vinay Mutthamsetty , Qinzhe Wang , Pravin Bhansali
- 申请人: The University of Toledo
- 申请人地址: US OH Toledo
- 专利权人: The University of Toledo
- 当前专利权人: The University of Toledo
- 当前专利权人地址: US OH Toledo
- 代理机构: MacMillan, Sobanski & Todd, LLC
- 国际申请: PCT/US2016/049208 WO 20160829
- 国际公布: WO2017/040376 WO 20170309
- 主分类号: A61K31/198
- IPC分类号: A61K31/198 ; C07C229/38 ; A61P25/28 ; A61P31/00 ; C07C227/18
摘要:
Phthalate derivatives that are aspartate-P-semialdehyde dehydrogenase (ASADH) inhibitor compounds, aspartate N-acetyltransferase (ANAT) inhibitor compounds, or both, are described, as well as methods of making the same, and methods of using the same.
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