专利检索 ap:("The University of Toledo") AND inv:"Bharani Thangavelu" 第 1 页

1.

发明授权
Potent inhibitors of aspartate N-acetyl-transferase for the treatment of Canavan disease 有权

公开(公告)号：US11186541B2

公开(公告)日：2021-11-30

申请号：US16088248

申请日：2017-03-23

申请人： The University of Toledo

发明人： Ronald E. Viola , Bharani Thangavelu , Vinay Mutthamsetty , Qinzhe Wang

IPC分类号： C07C233/51 , C07C229/36 , C07C269/06 , C07C271/22

摘要： Compounds, compositions, and methods for the treatment of Canavan disease are described.

2.

发明申请
POTENT PHTHALATE INHIBITORS OF ASPARTATE N-ACETYLTRANSFERASE AND SELECTIVE ASPARTATE PATHWAY INHIBITORS 审中-公开

公开(公告)号：US20180250252A1

公开(公告)日：2018-09-06

申请号：US15755447

申请日：2016-08-29

申请人： The University of Toledo

发明人： Ronald E. Viola , Bharani Thangavelu , Vinay Mutthamsetty , Qinzhe Wang , Pravin Bhansali

IPC分类号： A61K31/198 , A61P31/00 , C07C227/18 , A61P25/28

CPC分类号： A61K31/198 , A61P25/28 , A61P31/00 , C07C227/18 , C07C229/38 , Y02A50/475 , Y02A50/481

摘要： Phthalate derivatives that are aspartate-P-semialdehyde dehydrogenase (ASADH) inhibitor compounds, aspartate N-acetyltransferase (ANAT) inhibitor compounds, or both, are described, as well as methods of making the same, and methods of using the same.

3.

发明申请
POTENT INHIBITORS OF ASPARTATE N-ACETYL-TRANSFERASE FOR THE TREATMENT OF CANAVAN DISEASE 审中-公开

公开(公告)号：US20200270202A1

公开(公告)日：2020-08-27

申请号：US16088248

申请日：2017-03-23

申请人： The University of Toledo

发明人： Ronald E. Viola , Bharani Thangavelu , Vinay Mutthamsetty , Qinzhe Wang

IPC分类号： C07C233/51 , C07C271/22 , C07C229/36 , C07C269/06

摘要： Compounds, compositions, and methods for the treatment of Canavan disease are described.

4.

发明授权
Potent phthalate inhibitors of aspartate N-acetyltransferase and selective aspartate pathway inhibitors 有权

公开(公告)号：US10449168B2

公开(公告)日：2019-10-22

申请号：US15755447

申请日：2016-08-29

申请人： The University of Toledo

发明人： Ronald E. Viola , Bharani Thangavelu , Vinay Mutthamsetty , Qinzhe Wang , Pravin Bhansali

IPC分类号： A61K31/198 , C07C229/38 , A61P25/28 , A61P31/00 , C07C227/18

摘要： Phthalate derivatives that are aspartate-P-semialdehyde dehydrogenase (ASADH) inhibitor compounds, aspartate N-acetyltransferase (ANAT) inhibitor compounds, or both, are described, as well as methods of making the same, and methods of using the same.