- 专利标题： Sulfonyl amide derivatives for the treatment of abnormal cell growth
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申请号： US15946117申请日： 2018-04-05
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公开(公告)号： US10450297B2公开(公告)日： 2019-10-22
- 发明人: Michael J. Luzzio , Kevin D. Freeman-Cook , Samit K. Bhattacharya , Matthew M. Hayward , Catherine A. Hulford , Christopher L. Autry , Xumiao Zhao , Jun Xiao , Kendra L. Nelson
- 申请人： Pfizer, Inc.
- 申请人地址： US NY New York
- 专利权人： Pfizer, Inc.
- 当前专利权人： Pfizer, Inc.
- 当前专利权人地址： US NY New York
- 代理机构： Goodwin Procter LLP
- 主分类号： C07D401/12
- IPC分类号： C07D401/12 ; C07D239/48 ; C07D401/14 ; C07D403/12 ; C07D405/14 ; C07D413/14 ; C07D417/12 ; C07D417/14 ; C07D241/20 ; C07D475/00
摘要：
The present invention relates to a compound of the formula I wherein R1 to R6, A, B, n and m are as defined herein. Such novel sulfonyl amide derivatives are useful in the treatment of abnormal cell growth, such as cancer, in mammals. This invention also relates to a method of using such compounds in the treatment of abnormal cell growth in mammals, especially humans, and to pharmaceutical compositions containing such compounds.
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