Embodiments of the present disclosure provide a method and bus for accessing a dynamic random access memory (DRAM). The embodiments include receiving an access instruction, where the access instruction includes an access address, the access address includes a physical address, and a first field and a second field that are additionally set, the first field is used to indicate an interleaving mode, the interleaving mode indicates a manner of selecting an access channel, the second field is used to indicate an interleaving granularity, and the interleaving granularity indicates a capacity of an address space corresponding to the access channel; determining, according to the first field and the second field, the access channel and an address corresponding to the access channel; and accessing the DRAM according to the access channel and the address corresponding to the access channel.