Invention Grant
- Patent Title: Corneal epithelioid cells derived from surface ectodermal cells
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Application No.: US15543021Application Date: 2016-01-12
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Publication No.: US10457913B2Publication Date: 2019-10-29
- Inventor: Kohji Nishida , Yuzuru Sasamoto , Ryuhei Hayashi
- Applicant: Osaka University
- Applicant Address: JP Osaka
- Assignee: Osaka University
- Current Assignee: Osaka University
- Current Assignee Address: JP Osaka
- Agency: Foley & Lardner LLP
- Priority: JP2015-004389 20150113
- International Application: PCT/JP2016/050619 WO 20160112
- International Announcement: WO2016/114242 WO 20160721
- Main IPC: C12N5/071
- IPC: C12N5/071 ; C07K14/47 ; C12N15/86
Abstract:
The present invention relates to a method for inducing a keratin 12-positive corneal epithelioid cell from a surface ectoderm-derived cell. More specifically, the present invention relates to a method for inducing a keratin 12-positive corneal epithelioid cell, comprising introducing PAX6, KLF4, and OCT4 into a surface ectoderm-derived cell, such as an oral mucosal epithelial cell, and a corneal epithelioid cell induced by the method.
Public/Granted literature
- US20180148685A1 CORNEAL EPITHELIOID CELLS DERIVED FROM SURFACE ECTODERMAL CELLS Public/Granted day:2018-05-31
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