The disclosure provides methods and apparatuses for multiple user uplink. One aspect of the disclosure provides a method for wireless communication. The method comprises receiving a trigger frame from an access point indicating a target transmission duration for transmission of a physical layer (PHY) service data unit (PSDU) to the access point. The method also comprises generating an aggregated medium access control (MAC) packet data unit (A-MPDU) frame comprising at least one A-MPDU subframe, the A-MPDU frame having a first length, determining whether an additional A-MPDU subframe having a second length may be added to the A-MPDU frame based at least in part on the first length, the second length, and the target transmission duration, and including one or more padding subframes in the A-MPDU frame based at least in part on a comparison between the first length and the target transmission duration.