Invention Grant
- Patent Title: Imidazopyridazine compounds useful as modulators of IL-12, IL-23 and/or IFN alpha responses
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Application No.: US15776094Application Date: 2016-11-17
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Publication No.: US10479793B2Publication Date: 2019-11-19
- Inventor: David S. Weinstein , Ryan M. Moslin , Yanlei Zhang , Daniel S. Gardner , Joseph B. Santella , Charles M. Langevine , Sylwia Stachura
- Applicant: BRISTOL-MYERS SQUIBB COMPANY
- Applicant Address: US NJ Princeton
- Assignee: Bristol-Myers Squibb Company
- Current Assignee: Bristol-Myers Squibb Company
- Current Assignee Address: US NJ Princeton
- Agent Elliott Korsen
- International Application: PCT/US2016/062396 WO 20161117
- International Announcement: WO2017/087590 WO 20170526
- Main IPC: C07D487/04
- IPC: C07D487/04 ; A61P37/02 ; A61P29/00 ; A61K31/5025 ; A61K31/53 ; A61K31/5377

Abstract:
Compounds of formula I or a stereoisomer or pharmaceutically-acceptable salt thereof, are useful in the modulation of IL-12, IL-23 and/or IFNα, by acting on Tyk-2 to cause signal transduction inhibition.
Public/Granted literature
- US20180325899A1 IMIDAZOPYRIDAZINE COMPOUNDS USEFUL AS MODULATORS OF IL-12, IL-23 AND/OR IFN ALPHA RESPONSES Public/Granted day:2018-11-15
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