An audio amplifier circuit for providing an output signal to an audio transducer may include a power amplifier and a control circuit. The power amplifier may include an audio input for receiving an audio input signal, an audio output for generating the output signal based on the audio input signal, and a power supply input for receiving a power supply voltage, wherein the power supply voltage is variable among at least a first supply voltage and a second supply voltage greater than the first supply voltage and wherein the power supply voltage is generated by a configurable charge pump power supply. The control circuit may be configured to predict, based on one or more characteristics of a signal indicative of the output signal, an occurrence of a condition for changing the power supply voltage, and responsive to predicting the occurrence of the condition, change, at an approximate zero crossing of the signal indicative of the output signal, the power supply voltage.