Invention Grant
- Patent Title: 6-hydroxy-5-(phenyl/heteroarylsulfonyl)pyrimidin-4(1H)-one as APJ agonists
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Application No.: US16309161Application Date: 2017-06-14
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Publication No.: US10508104B2Publication Date: 2019-12-17
- Inventor: George O. Tora , Heather Finlay , Wen Jiang , Wei Meng , Xiaojun Zhang
- Applicant: Bristol-Myers Squibb Company
- Applicant Address: US NJ Princeton
- Assignee: Bristol-Myers Squibb Company
- Current Assignee: Bristol-Myers Squibb Company
- Current Assignee Address: US NJ Princeton
- Agent Hong Liu
- International Application: PCT/US2017/037405 WO 20170614
- International Announcement: WO2017/218633 WO 20171221
- Main IPC: C07D405/04
- IPC: C07D405/04 ; C07D403/12 ; C07D401/14 ; C07D405/14 ; C07D401/04 ; C07D401/06 ; C07D401/12 ; C07D405/06 ; C07D405/12 ; C07D409/12 ; C07D239/60 ; C07D413/12 ; C07D417/12 ; C07D471/04 ; A61P9/10 ; A61P9/04
Abstract:
The present invention provides compounds of Formula (I): wherein all variables are as defined in the specification, and compositions comprising any of such novel compounds. These compounds are APJ agonists which may be used as medicaments.
Public/Granted literature
- US20190194173A1 6-HYDROXY-5-(PHENYL/HETEROARYLSULFONYL)PYRIMIDIN-4(1H)-ONE AS APJ AGONISTS Public/Granted day:2019-06-27
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