Invention Grant
- Patent Title: Survivin-targeting anti-tumor agents and uses thereof
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Application No.: US15573867Application Date: 2016-05-13
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Publication No.: US10517871B2Publication Date: 2019-12-31
- Inventor: Jian-Ting Zhang , Jing-Yuan Liu
- Applicant: Indiana University Research and Technology Corporation
- Applicant Address: US IN Indianapolis
- Assignee: Indiana University Research and Technology Corporation
- Current Assignee: Indiana University Research and Technology Corporation
- Current Assignee Address: US IN Indianapolis
- Agency: Faegre Baker Daniels LLP
- International Application: PCT/US2016/032473 WO 20160513
- International Announcement: WO2016/187046 WO 20161124
- Main IPC: A61K31/4985
- IPC: A61K31/4985 ; A61P35/02 ; G01N33/50
Abstract:
Methods for treating various cancers by administering one or more compounds that target the dimeric protein survivin are disclosed. Pharmaceutical compositions containing such compounds are also disclosed, along with general methods of identifying anti-cancer compounds that target oncogenic dimeric proteins. Exemplary compounds that can be used in the disclosed methods of treatment and pharmaceutical compositions have the chemical structure.
Public/Granted literature
- US20180296557A1 SURVIVIN-TARGETING ANTI-TUMOR AGENTS AND USES THEREOF Public/Granted day:2018-10-18
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