Invention Grant
- Patent Title: KRAS G12C inhibitors and methods of using the same
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Application No.: US15849905Application Date: 2017-12-21
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Publication No.: US10532042B2Publication Date: 2020-01-14
- Inventor: Brian Alan Lanman , Victor J. Cee , Alexander J. Pickrell , Anthony B. Reed , Kevin C. Yang , David John Kopecky , Hui-Ling Wang , Patricia Lopez , Kate Ashton , Shon Booker , Christopher M. Tegley
- Applicant: AMGEN INC.
- Applicant Address: US CA Thousand Oaks
- Assignee: Amgen Inc.
- Current Assignee: Amgen Inc.
- Current Assignee Address: US CA Thousand Oaks
- Agent Joseph F. Reidy
- Main IPC: C07D487/04
- IPC: C07D487/04 ; A61K31/428 ; A61K31/496 ; A61K31/519 ; A61P35/00 ; A61K31/5025 ; A61K31/502 ; A61K31/517 ; C07D401/04 ; C07D403/04 ; C07D239/80 ; C07D417/04 ; C07D471/04 ; C07D471/08 ; C07D487/10 ; C07D275/04 ; C07D513/04
Abstract:
Provided herein are KRAS G12C inhibitors, compounds of formula (II), or a pharmaceutically acceptable salt thereof: compositions of the same, and methods of using the same. These inhibitors are useful for treating a number of disorders, including pancreatic, colorectal, and lung cancers.
Public/Granted literature
- US20180177767A1 KRAS G12C INHIBITORS AND METHODS OF USING THE SAME Public/Granted day:2018-06-28
Information query
