- 专利标题: Stabilization of glutamate dehydrogenase in an aqueous solution
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申请号: US15038554申请日: 2014-12-08
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公开(公告)号: US10533999B2公开(公告)日: 2020-01-14
- 发明人: Florence Bettsworth , Jérôme Martinez
- 申请人: BIOMERIEUX
- 申请人地址: FR Marcy L'Etoile
- 专利权人: BIOMERIEUX
- 当前专利权人: BIOMERIEUX
- 当前专利权人地址: FR Marcy L'Etoile
- 代理机构: Oliff PLC
- 优先权: FR1362354 20131210
- 国际申请: PCT/FR2014/053213 WO 20141208
- 国际公布: WO2015/086973 WO 20150618
- 主分类号: C12N1/32
- IPC分类号: C12N1/32 ; G01N33/573 ; C12N9/06 ; C12N9/96 ; C12Q1/04 ; C12Q1/32
摘要:
A process for stabilizing glutamate dehydrogenase (GDH) from a bacterium of the Clostridium genus, in an aqueous solution, in order to maintain the antigenic properties thereof, includes the step of mixing the glutamate dehydrogenase and a stabilizing composition which is a carboxylic acid having a carbon-based chain of at least 3 carbon atoms and comprising at least 2 —COOH groups, or a salt thereof. GDH compositions thus stabilized and a method of detecting the presence of bacteria of the Clostridium genus are also disclosed.
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