- 专利标题： Heteroaryls and uses thereof
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申请号： US15665506申请日： 2017-08-01
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公开(公告)号： US10538533B2公开(公告)日： 2020-01-21
- 发明人: Indu T. Bharathan , Chris Blackburn , Jeffrey P. Ciavarri , Jouhara Chouitar , Courtney A. Cullis , Natalie D'Amore , Paul E. Fleming , Kenneth M. Gigstad , Krista E. Gipson , Mario Girard , Yongbo Hu , Janice Lee , Gang Li , Mansoureh Rezaei , Michael D. Sintchak , Francois Soucy , Stephen G. Stroud , Tricia J. Vos , Tzu-Tshin Wong , He Xu , Tianlin Xu , Yingchun Ye
- 申请人： Millennium Pharmaceuticals, Inc.
- 申请人地址： US MA Cambridge
- 专利权人： Millennium Pharmaceuticals, Inc.
- 当前专利权人： Millennium Pharmaceuticals, Inc.
- 当前专利权人地址： US MA Cambridge
- 代理机构： Sterne, Kessler, Goldstein & Fox P.L.L.C.
- 主分类号： C07D513/04
- IPC分类号： C07D513/04 ; C07D401/04 ; A61K31/444 ; A61K45/06 ; C07D417/14 ; C07D401/14 ; A61K31/506 ; C07D471/04 ; A61K31/437 ; A61K31/549 ; A61K31/497
摘要：
The present invention provides a compound of formula I: and pharmaceutically acceptable salts thereof, wherein X, R1, R2, R3, R4, R5, L1, L2, m, and n, are as described in the specification. Such compounds are inhibitors of VPS34 and thus useful for treating proliferative, inflammatory, or cardiovascular disorders.
公开/授权文献
- US20180118762A1 HETEROARYLS AND USES THEREOF 公开/授权日：2018-05-03
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