Methods, devices, systems, and series of appliances are provided for dental implant positioning. One method for positioning an implant with dental treatment includes determining an implant location based on a virtual model of an optimized dental occlusion, moving one or more teeth using a first number of a series of dental appliances, from a first orientation to a second orientation, the second orientation exposing the implant location, placing an implant at the exposed implant location using a landmark included in at least one of the series of dental appliances, repositioning one or more teeth using a second number of the series of dental appliances, from the second orientation to a successive orientation.