Invention Grant
- Patent Title: Tumor selective macropinocytosis-dependent rapidly internalizing antibodies
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Application No.: US15321684Application Date: 2015-07-09
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Publication No.: US10550195B2Publication Date: 2020-02-04
- Inventor: Bin Liu
- Applicant: The Regents of The University of California
- Applicant Address: US CA Oakland
- Assignee: The Regents of the University of California
- Current Assignee: The Regents of the University of California
- Current Assignee Address: US CA Oakland
- Agency: Weaver Austin Villeneuve & Sampson LLP
- Agent Tom Hunter
- International Application: PCT/US2015/039741 WO 20150709
- International Announcement: WO2016/007741 WO 20160114
- Main IPC: C40B40/10
- IPC: C40B40/10 ; C07K16/30 ; A61K45/06 ; A61K49/00 ; C07K16/00
Abstract:
Methods are provided for identifying and selecting antibodies that are internalized into cells via the macropinocytosis pathway. Additionally antibodies that are internalized via this pathway are provided as well as immunoconjugates comprising such antibodies.
Public/Granted literature
- US20170137532A1 TUMOR SELECTIVE MACROPINOCYTOSIS-DEPENDENT RAPIDLY INTERNALIZING ANTIBODIES Public/Granted day:2017-05-18
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