Invention Grant
- Patent Title: Humanized antibodies against CEACAM1
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Application No.: US15306664Application Date: 2015-04-27
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Publication No.: US10550196B2Publication Date: 2020-02-04
- Inventor: Tehila Ben-Moshe , Yair Sapir , Ilana Mandel , Gal Markel , Jacob Schachter , Rona Ortenberg , Francis Joseph Carr , Robert George E. Holgate , Timothy David Jones
- Applicant: CCAM BIOTHERAPEUTICS LTD.
- Applicant Address: IL Tel Aviv
- Assignee: Famewave Ltd.
- Current Assignee: Famewave Ltd.
- Current Assignee Address: IL Tel Aviv
- Agency: Rothwell, Figg, Ernst & Manbeck, P.C.
- International Application: PCT/IL2015/050433 WO 20150427
- International Announcement: WO2015/166484 WO 20151105
- Main IPC: C07K16/42
- IPC: C07K16/42 ; C07K16/30 ; A61K35/17 ; A61K39/395 ; A61K45/06 ; G01N33/68 ; A61K39/00 ; G01N33/574 ; C07K16/28

Abstract:
Humanized antibodies, capable of specific binding to human CEACAM1 molecules containing human-to-murine back-mutations in non-CDR variable regions, and their encoding polynucleotide sequences are provided. Pharmaceutical compositions comprising these antibodies as well as methods of their use in treating and diagnosing cancer and other conditions are also provided.
Public/Granted literature
- US20170044270A1 HUMANIZED ANTIBODIES AGAINST CEACAM1 Public/Granted day:2017-02-16
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