Invention Grant
- Patent Title: Compositions and methods for delivery of agents
-
Application No.: US15674107Application Date: 2017-08-10
-
Publication No.: US10556018B2Publication Date: 2020-02-11
- Inventor: Gilles Besin , Stephen Hoge , Joseph Senn , Kerry Benenato , Staci Sabnis
- Applicant: ModernaTX, Inc.
- Agency: Wolf, Greenfield & Sacks, P.C.
- Main IPC: A61K48/00
- IPC: A61K48/00 ; A61K9/127 ; C12N15/88 ; A61K47/54 ; A61K47/69 ; A61K47/60 ; A61K31/713 ; A61K39/39 ; A61K47/10 ; C08G65/332 ; C08G65/333 ; C08G65/334 ; C08G65/335 ; C12N15/117 ; A61K31/7115 ; A61K47/14 ; A61K47/18 ; A61K39/00
Abstract:
This disclosure provides improved lipid-based compositions, including lipid nanoparticle compositions, and methods of use thereof for delivering agents in vivo including nucleic acids and proteins. These compositions are not subject to accelerated blood clearance and they have an improved toxicity profile in vivo.
Public/Granted literature
- US20180147298A1 COMPOSITIONS AND METHODS FOR DELIVERY OF AGENTS Public/Granted day:2018-05-31
Information query
