Invention Grant
- Patent Title: Molecular sensor and methods of use thereof
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Application No.: US15640545Application Date: 2017-07-02
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Publication No.: US10557853B2Publication Date: 2020-02-11
- Inventor: David Margulies , Leila Motiei , Linor Unger
- Applicant: YEDA RESEARCH AND DEVELOPMENT CO. LTD.
- Applicant Address: IL Rehovot
- Assignee: YEDA RESEARCH AND DEVELOPMENT CO. LTD.
- Current Assignee: YEDA RESEARCH AND DEVELOPMENT CO. LTD.
- Current Assignee Address: IL Rehovot
- Agency: Zedek Latzer Baratz LLP
- Agent Mark S. Cohen; Pearl Cohen
- Main IPC: C07D417/06
- IPC: C07D417/06 ; G01N33/58 ; C07D417/14 ; C07K7/06 ; C09K11/06 ; G01N33/573 ; G01N33/574

Abstract:
The present invention is directed to fluorescent molecular sensor based on Thiazole Orange for protein detection. Interaction of the protein target with the molecular sensors of this invention results in a significant increase in the fluorescence emission. The generation of light output signal enables one to detect protein biomarkers associated with different diseases or detecting the protein of interest also in living cells.
Public/Granted literature
- US20170307625A1 MOLECULAR SENSOR AND METHODS OF USE THEREOF Public/Granted day:2017-10-26
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