Invention Grant
- Patent Title: Biomarkers for risk prediction of mortality
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Application No.: US15581587Application Date: 2017-04-28
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Publication No.: US10557858B2Publication Date: 2020-02-11
- Inventor: Roberto Latini , Serge Masson , Dirk Block , Christian Zaugg , Thomas Dieterle , Edelgard Kaiser , Johann Karl , Vinzent Rolny , Ursula-Henrike Wienhues-Thelen
- Applicant: Roche Diagnostics Operations, Inc.
- Applicant Address: US IN Indianapolis
- Assignee: Roche Diagnostics Operations, Inc.
- Current Assignee: Roche Diagnostics Operations, Inc.
- Current Assignee Address: US IN Indianapolis
- Agency: Roche Diagnostics Operations, Inc.
- Priority: EP14190836 20141029; EP14192653 20141111
- Main IPC: G01N33/50
- IPC: G01N33/50 ; G01N33/68
Abstract:
Described is a method for predicting the risk of a subject of rapidly progressing to chronic heart failure and/or of hospitalization due to chronic heart failure and/or death. The method is based on the determination of at least one biomarker selected from B-type natriuretic peptide (BNP) or N-terminal pro B-type natriuretic peptide (NT-proBNP), IGFBP7 (IGF binding protein 7), a cardiac Troponin, soluble ST2 (sST2), FGF-23 (Fibroblast Growth Factor 23), and Growth Differentiation Factor 15 (GDF-15), in a sample of a subject along with the assessment of the presence or absence of (i) abnormal midwall fractional shortening or (ii) left ventricular hypertrophy.
Public/Granted literature
- US20170227552A1 BIOMARKERS FOR RISK PREDICTION OF MORTALITY Public/Granted day:2017-08-10
Information query
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