发明授权
- 专利标题： Inhibition and treatment of bacterial infections by sex-specific GPER targeting
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申请号： US16067721申请日： 2017-01-09
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公开(公告)号： US10561648B2公开(公告)日： 2020-02-18
- 发明人: Pamela Hall , Eric R. Prossnitz , Helen J. Hathaway
- 申请人： STC.UNM
- 申请人地址： US NM Albuquerque
- 专利权人： STC.UNM
- 当前专利权人： STC.UNM
- 当前专利权人地址： US NM Albuquerque
- 代理商 Henry D. Colemam; R. Neil Sudol
- 国际申请： PCT/US2017/012687 WO 20170109
- 国际公布： WO2017/123492 WO 20170720
- 主分类号： A61K31/473
- IPC分类号： A61K31/473 ; A61K45/06 ; A61K35/644 ; A61K38/14 ; C07K14/705 ; A61K31/4741 ; A61P31/04
摘要：
The present invention is directed to the use of compounds which are modulators of the G protein-Coupled Estrogen Receptor (GPER) for the inhibition —and/or treatment of Bacterial infections, especially including metMctHin-resistant Staphylococcus aureus (MRSA) infections. Pharmaceutical compositions and methods of treatment of bacterial pathogens, including MRSA are also described.
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