A system comprises a memory device comprising a plurality of memory cells; and a processing device coupled to the memory device, the processing device configured to iteratively: determine a set of read results based on reading a subset of memory cells according to read levels maintained within optimization trim data, wherein the optimization trim data initially comprises at least one read level in addition to a target trim; calibrate the set of read levels based on the set of read results; and remove the calibrated read levels from the optimization trim data when the calibrated read levels satisfy a calibration condition.