An interference suppression method, apparatus, and system to suppress interference between an uplink signal and a downlink signal, and improve communication quality. The method includes determining, by a first base station, control channel indication information of a first cell, where the first cell is any one of cells managed by the first base station, and the control channel indication information includes at least one piece of the following information of control channel indication information of a contradirectional-transmission frequency band on which the first cell is interfered with by a neighboring cell, or control channel indication information of a contradirectional-transmission subframe in which the first cell is interfered with by a neighboring cell, and sending, by the first base station, the control channel indication information to a second base station, where the second base station is a base station of the neighboring cell.