Systems, apparatuses, and methods for tracking page reuse and migrating pages are disclosed. In one embodiment, a system includes one or more processors, a memory access monitor, and multiple memory regions. The memory access monitor tracks accesses to memory pages in a system memory during a programmable interval. If the number of accesses to a given page is greater than a programmable threshold during the programmable interval, then the memory access monitor generates an interrupt for software to migrate the given page from the system memory to a local memory. If the number of accesses to the given page is less than or equal to the programmable threshold during the programmable interval, then the given page remains in the system memory. After the programmable interval, the memory access monitor starts tracking the number of accesses to a new page in a subsequent interval.