Disclosed herein are system, method, and computer program product embodiments for an application set-up and management system (AMS). An embodiment operates by receiving a selection of an application for installation. The application accesses a plurality of data fields during its execution, including both a first set of one or more of the data fields that are managed on a centralized database, and a second set of one or more of the data fields that are managed on a decentralized ledger during its operation. The application is installed on a cloud platform of a first user account, wherein the cloud platform includes access to the centralized database. Information associated with setting up the decentralized ledger corresponding to the application is received, and the decentralized ledger is set up. The application is activated on the cloud platform.