- Patent Title: Compounds and compositions for the treatment of parasitic diseases
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Application No.: US16116418Application Date: 2018-08-29
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Publication No.: US10596175B2Publication Date: 2020-03-24
- Inventor: Agnes Biggart , Fang Liang , Casey Jacob Nelson Mathison , Valentina Molteni , Advait Suresh Nagle , Frantisek Supek , Vince Yeh
- Applicant: NOVARTIS AG
- Applicant Address: CH Basel
- Assignee: Novartis AG
- Current Assignee: Novartis AG
- Current Assignee Address: CH Basel
- Agency: Genomics Institute of the Novartis Research Foundation
- Agent Emily T. Wu
- Main IPC: C07D487/04
- IPC: C07D487/04 ; A61K31/519 ; C07D519/00 ; C07F5/02 ; C07F7/08 ; A61K31/5377 ; A61K31/695 ; A61K45/06

Abstract:
The present invention provides compounds of Formula A: or a pharmaceutically acceptable salt, tautomer, or stereoisomer, thereof, wherein the variables are as defined herein. The present invention further provides pharmaceutical compositions comprising such compounds and methods of using such compounds for treating, preventing, inhibiting, ameliorating, or eradicating the pathology and/or symptomology of a disease caused by a parasite, such as leishmaniasis, human African trypanosomiasis and Chagas disease.
Public/Granted literature
- US20190000852A1 COMPOUNDS AND COMPOSITIONS FOR THE TREATMENT OF PARASITIC DISEASES Public/Granted day:2019-01-03
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