- 专利标题: Anthelmintic compounds, compositions and method of using thereof
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申请号: US15544837申请日: 2016-01-20
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公开(公告)号: US10597364B2公开(公告)日: 2020-03-24
- 发明人: Alan Long , Douglas Edward Wilkinson
- 申请人: BOEHRINGER INGELHEIM ANIMAL HEALTH USA INC.
- 申请人地址: US GA Duluth
- 专利权人: BOEHRINGER INGELHEIM ANIMAL HEALTH USA INC.
- 当前专利权人: BOEHRINGER INGELHEIM ANIMAL HEALTH USA INC.
- 当前专利权人地址: US GA Duluth
- 代理商 Judy Jarecki-Black; Katrina Bergbauer
- 国际申请: PCT/US2016/014148 WO 20160120
- 国际公布: WO2016/118638 WO 20160728
- 主分类号: C07D487/04
- IPC分类号: C07D487/04 ; C07D213/74 ; C07D405/12 ; C07D401/12 ; C07D417/12 ; C07D409/12 ; A61K31/496 ; A61K45/06
摘要:
The present invention relates to novel anthelmintic compounds of formula (IA) below: wherein, Y is selected from the group consisting of —H, aryl, cycloalkyl, cycloalkenyl, heteroaryl, heterocyclyl, alkyl, haloalkyl, and alkoxyalkyl; and Z is selected from the group consisting of aryl, cycloalkyl, cycloalkenyl, heteroaryl, heterocyclyl, alkyl, haloalkyl, and alkoxyalkyl. Variables Ring A, Ring B, Ring C, X1, X6, and X8 are as defined herein. The invention also relates to parasiticidal compositions comprising the compounds, and methods and uses of the compounds for treating and preventing parasitic infections and infestations in animals.
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