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公开(公告)号：US11964977B2
公开(公告)日：2024-04-23
申请号：US17324288
申请日：2021-05-19
发明人： Hannes Fiepko Koolman , Bart Herlé , Alan Long
IPC分类号： A61K31/5025 , A61P33/10 , C07D487/04
CPC分类号： C07D487/04 , A61P33/10
摘要： This invention provides for compounds of the formula:
wherein the variables are defined herein, or salt thereof, compositions comprising these compounds, and method for the treatment, control or prevention of a parasitic infestation or infection in an animal in need thereof by administering an effective amount of these compounds to said animal.-
公开(公告)号：US20190307838A1
公开(公告)日：2019-10-10
申请号：US16461741
申请日：2017-11-15
摘要： The present invention provides cyclic depsipeptide compounds of formula (I) wherein the stereochemical configuration of at least one carbon atom bearing the groups Cy1, Cy2, R1, R2, R3, R4, Ra and Rb is inverted compared with the naturally occurring cyclic depsipeptide PF1022A. The invention also provides compositions comprising the compounds that are effective against parasites that harm animals. The compounds and compositions may be used for combating parasites in or on mammals and birds. The invention also provides for an improved method for eradicating, controlling and preventing parasite infestation in birds and mammals.
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公开(公告)号：US20190281829A1
公开(公告)日：2019-09-19
申请号：US16340795
申请日：2017-10-11
IPC分类号： A01N43/80 , A61P33/14 , C07D261/04 , C07D471/04 , A01N43/90
摘要： The present invention relates to pesticidal and parasiticidal isoxazoline of formula (I) and salts thereof: wherein variables B1, B2, B3, R1, P1, P2, Y and Q are described herein are as defined in the description. The invention also relates to parasiticidal and pesticidal compositions comprising the isoxazoline compounds of formula (I), processes for their preparation and their uses to prevent or treat parasitic infections or infestations in animals and as pesticides.
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公开(公告)号：US20220098241A1
公开(公告)日：2022-03-31
申请号：US17643251
申请日：2021-12-08
IPC分类号： C07K11/02 , C07D413/14 , A01N43/72 , C07D273/00 , A61K38/15 , A61K45/06
摘要： The present invention provides cyclic depsipeptide compounds of formula (I) and compositions comprising the compounds that are effective against parasites that harm animals, including humans. The compounds and compositions may be used for combating parasites in or on animals including mammals and birds. The invention also provides for an improved method for eradicating, controlling and preventing parasite infestation in animals, including birds and mammals.
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公开(公告)号：US11230571B2
公开(公告)日：2022-01-25
申请号：US16392412
申请日：2019-04-23
IPC分类号： C07K11/02 , A61K38/15 , A61K45/06 , A61P33/00 , A61P33/10 , A61P43/00 , C07D413/14 , A01N43/72 , C07D273/00
摘要： The present invention provides cyclic depsipeptide compounds of formula (I) and compositions comprising the compounds that are effective against parasites that harm animals, including humans. The compounds and compositions may be used for combating parasites in or on animals including mammals and birds. The invention also provides for an improved method for eradicating, controlling and preventing parasite infestation in animals, including birds and mammals.
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公开(公告)号：US10793604B2
公开(公告)日：2020-10-06
申请号：US16111027
申请日：2018-08-23
发明人： Loic Le Hir de Fallois , Greg Pacofsky , Alan Long , Charles Meng , Hyoung Ik Lee , Cyprian O. Ogbu
IPC分类号： C07K11/02 , A01N43/72 , C07D273/00 , A61K38/00
摘要： The present invention provides cyclic depsipeptide compounds of formula (I) and compositions comprising the compounds that are effective against parasites that harm animals. The compounds and compositions may be used for combating parasites in or on mammals and birds. The invention also provides for an improved method for eradicating, controlling and preventing parasite infestation in birds and mammals.
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公开(公告)号：US20190248840A1
公开(公告)日：2019-08-15
申请号：US16392412
申请日：2019-04-23
IPC分类号： C07K11/02 , A61K45/06 , A61K38/15 , C07D413/14 , A01N43/72 , C07D273/00
CPC分类号： C07K11/02 , A01N43/72 , A61K38/15 , A61K45/06 , C07D273/00 , C07D413/14
摘要： The present invention provides cyclic depsipeptide compounds of formula (I) and compositions comprising the compounds that are effective against parasites that harm animals, including humans. The compounds and compositions may be used for combating parasites in or on animals including mammals and birds. The invention also provides for an improved method for eradicating, controlling and preventing parasite infestation in animals, including birds and mammals.
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公开(公告)号：US10344056B2
公开(公告)日：2019-07-09
申请号：US15378219
申请日：2016-12-14
IPC分类号： A61P33/00 , C07K11/02 , A61K38/15 , A61K45/06 , C07D413/14 , A01N43/72 , C07D273/00
摘要： The present invention provides cyclic depsipeptide compounds of formula (I) and compositions comprising the compounds that are effective against parasites that harm animals, including humans. The compounds and compositions may be used for combating parasites in or on animals including mammals and birds. The invention also provides for an improved method for eradicating, controlling and preventing parasite infestation in animals, including birds and mammals.
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公开(公告)号：US12018048B2
公开(公告)日：2024-06-25
申请号：US17643251
申请日：2021-12-08
IPC分类号： C07K11/02 , A01N43/72 , A61K38/15 , A61K45/06 , A61P33/10 , A61P43/00 , C07D273/00 , C07D413/14
CPC分类号： C07K11/02 , A01N43/72 , A61K38/15 , A61K45/06 , C07D273/00 , C07D413/14
摘要： Cyclic depsipeptide compounds of formula (I) and compositions comprising the compounds are provided that are effective against parasites that harm animals, including humans. The compounds and compositions may be used for combating parasites in or on animals including mammals and birds. Also provided are improved methods for eradicating, controlling and preventing parasite infestation in animals, including birds and mammals.
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公开(公告)号：US11589586B2
公开(公告)日：2023-02-28
申请号：US16638957
申请日：2018-08-14
发明人： Alan Long , Hyoung Ik Lee
IPC分类号： A01N43/80 , A01N43/90 , C07D413/04 , C07D491/107
摘要： The present invention relates to pesticidal and parasiticidal isoxazoline of formula (I) and salts thereof: wherein variables R1, P, Y and Q are described herein are as defined in the description. The invention also relates to parasiticidal and pesticidal compositions comprising the isoxazoline compounds of formula (I), processes for their preparation and their uses to prevent or treat parasitic infections or infestations in animals and as pesticides.
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