A shipping vessel includes a cryogenic tank secured to the shipping foundation; a payload bay to receive products therein; a tube connected to the cryogenic tank and thermally coupled to the payload bay; a housing secured to the shipping foundation, said housing covering the tube and the payload bay to thermally seal the payload bay from outside environment; a controller mounted on the housing and having a sensor to determine temperature in a closed-loop and maintaining a set point within a predetermined range; and an energy storage device coupled to the controller and electronics to provide power for a predetermined shipping period.