- 专利标题: Yeast strain having improved capability for fermenting xylose in the presence of acetic acid
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申请号: US15568188申请日: 2016-04-27
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公开(公告)号: US10604735B2公开(公告)日: 2020-03-31
- 发明人: Jean-Michel Bavouzet , Thomas Desfougeres , Georges Pignede , Jennifer Techel
- 申请人: LESAFFRE ET COMPAGNIE
- 申请人地址: FR Paris
- 专利权人: LESAFFRE et COMPAGNIE
- 当前专利权人: LESAFFRE et COMPAGNIE
- 当前专利权人地址: FR Paris
- 代理机构: Marshall, Gerstein & Borun LLP
- 优先权: FR1553760 20150427
- 国际申请: PCT/FR2016/050987 WO 20160427
- 国际公布: WO2016/174349 WO 20161103
- 主分类号: C12N1/14
- IPC分类号: C12N1/14 ; C12N9/92 ; C12P7/06 ; C12P7/04 ; C12N1/18 ; C12N1/36 ; C12R1/865 ; C12N1/16 ; C12P7/10
摘要:
The invention relates to a method for selecting a yeast strain having improved capability for fermenting a pentose, advantageously xylose, in the presence of organic acid, advantageously acetic acid, in non-dissociated form, in which at least one yeast strain that is capable of fermenting said pentose is consecutively cultured in the following two media: a first growth medium comprising said pentose as the only carbon source and said organic acid in non-dissociated form; a second growth medium comprising another carbon source as the only carbon source, advantageously glucose, free of said organic acid in non-dissociated form, the consecutive culture in at least said two growth media being repeated at least twice, in the presence of rising concentrations of organic acid in non-dissociated form.
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