Provided are multiuser communication methods and devices for Code Division Multiple Access (CDMA). N modulated symbols which are obtained by modulating a code block coded by a channel coder are acquired, where N is a positive integer more than or equal to 2. The N modulated symbols are spread according to N spread sequences with a specified length, and there may be at least two different spread sequences in the N spread sequences with the specified length. The spread modulated symbols are transmitted.