- 专利标题： Pyrimidine derivative, method for preparing same and use thereof in medicine
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申请号： US16302310申请日： 2017-05-19
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公开(公告)号： US10654836B2公开(公告)日： 2020-05-19
- 发明人: Lei Chen , Dongliang Guan , Hua Bai , Jun Gou , Weifeng Zhao , Zhongli Wang , Long Ling , Yutao Ma
- 申请人： Zhejiang Hisun Pharmaceutical Co., Ltd.
- 申请人地址： CN
- 专利权人： Zhejiang Hisun Pharmaceutical Co., Ltd.
- 当前专利权人： Zhejiang Hisun Pharmaceutical Co., Ltd.
- 当前专利权人地址： CN
- 代理机构： Lerner, David, Littenberg, Krumholz & Mentlik, LLP
- 优先权： com.zzzhc.datahub.patent.etl.us.BibliographicData$PriorityClaim@4884d80f
- 国际申请： PCT/CN2017/085135 WO 20170519
- 国际公布： WO2017/198221 WO 20171123
- 主分类号： C07D403/14
- IPC分类号： C07D403/14 ; C07D403/12 ; C07D471/10 ; C07D487/10 ; A61K31/506 ; A61P35/00 ; C07D403/04
摘要：
The present invention relates to a pyrimidine derivative, a method for preparing same and use thereof in medicine. In particular, the present invention relates to a pyrimidine derivative represented by general formula (I), a method for preparing same and a pharmaceutically acceptable salt thereof as well as use thereof as a therapeutic agent, in particular as a FGFR4 kinase inhibitor, definitions of each substituent in the general formula (I) being the same as those defined in the description.
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