- 专利标题: Anti-laminin4 antibodies specific for LG4-5
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申请号: US15991998申请日: 2018-05-29
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公开(公告)号: US10654920B2公开(公告)日: 2020-05-19
- 发明人: Stephen Jed Tam , Yue Liu , Robin Barbour , Theodore Yednock , Kenneth Flanagan
- 申请人: PROTHENA BIOSCIENCES LIMITED
- 申请人地址: IE Dublin
- 专利权人: PROTHENA BIOSCIENCES LIMITED
- 当前专利权人: PROTHENA BIOSCIENCES LIMITED
- 当前专利权人地址: IE Dublin
- 代理机构: Alston & Bird LLP
- 主分类号: G01N33/574
- IPC分类号: G01N33/574 ; C07K16/18 ; A61K47/68 ; A61K39/00
摘要:
The invention provides antibodies that specifically bind to the LG4-5 modules of the G domain of laminin α4. The antibodies can preferentially stain cancer or tumor cells or tissue. The antibodies can be used for detecting cancer, evaluating the efficacy of a cancer therapy, treating cancer, and treating obesity or obesity-related diseases, among other applications.
公开/授权文献
- US20180371067A1 ANTI-LAMININ4 ANTIBODIES SPECIFIC FOR LG4-5 公开/授权日:2018-12-27
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