Invention Grant
- Patent Title: Solid state forms of fused heteroaromatic pyrrolidinones
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Application No.: US14973180Application Date: 2015-12-17
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Publication No.: US10676473B2Publication Date: 2020-06-09
- Inventor: Rongliang Chen , Tomonori Ichibakase , Chunrong Ma , Christopher F. Matthews , Hajime Motoyoshi , Colin O'Bryan , Kentaro Yaji , Naoki Yoshikawa
- Applicant: TAKEDA PHARMACEUTICAL COMPANY LIMITED
- Applicant Address: JP Osaka
- Assignee: TAKEDA PHARMACEUTICAL COMPANY LIMITED
- Current Assignee: TAKEDA PHARMACEUTICAL COMPANY LIMITED
- Current Assignee Address: JP Osaka
- Agency: Jones Day
- Main IPC: C07D471/04
- IPC: C07D471/04 ; A61K9/20 ; A61K9/48

Abstract:
Disclosed are chemical entities which are inhibitors of spleen tyrosine kinase (SYK), namely, chemical entities comprising 6-((1R,2S)-2-aminocyclohexylamino)-7-fluoro-4-(1-methyl-1H-pyrazol-4-yl)-1H-pyrrolo[3,4-c]pyridine-3(2H)-one and certain solid state forms thereof. Also disclosed are methods of using the chemical entities to treat disorders such as a cancer.
Public/Granted literature
- US20160176869A1 Solid State Forms of Fused Heteroaromatic Pyrrolidinones Public/Granted day:2016-06-23
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