Invention Grant
- Patent Title: Biomarkers for risk assessment and treatment monitoring in heart failure patients guided by natriuretic peptides
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Application No.: US15220555Application Date: 2016-07-27
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Publication No.: US10684291B2Publication Date: 2020-06-16
- Inventor: Dirk Block , Hans-Peter Brunner , Ursula-Henrike Wienhues-Thelen , Christian Zaugg , Thomas Dieterle , Cheryl Mitchell , Johan Ubby , Sandra Sanders-van Wijk
- Applicant: Roche Diagnostics Operations, Inc.
- Applicant Address: US IN Indianapolis
- Assignee: Roche Diagnostics Operations, Inc.
- Current Assignee: Roche Diagnostics Operations, Inc.
- Current Assignee Address: US IN Indianapolis
- Agency: Roche Diagnostics Operations, Inc.
- Priority: com.zzzhc.datahub.patent.etl.us.BibliographicData$PriorityClaim@42cd8432
- Main IPC: G01N33/53
- IPC: G01N33/53 ; G01N33/68 ; G01N33/62 ; G01N33/66 ; G01N33/70 ; G01N33/72 ; G01N33/84

Abstract:
The present description relates to a method for identifying a patient who is eligible for an intensification of heart failure therapy. Furthermore, the description relates to a method for optimizing B type natriuretic peptide (BNP) and/or N-terminal pro B-type natriuretic peptide (NT-proBNP)-type peptide guided heart failure therapy. The methods are based on the measurement of the level of at least one marker in a sample from a patient who has heart failure and who receives B-type natriuretic peptide (BNP) and/or N-terminal pro B-type natriuretic peptide (NT-proBNP)-type peptide guided heart failure therapy. Further described are kits and devices adapted to carry out the described method.
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