An optimized non-volatile memory operating method. A data storage device has a plurality of non-volatile memory spaces and a plurality of command queues. The command queues are provided to correspond to the non-volatile storage memory one on one. The same channel is shared to operate the non-volatile memory spaces. To deal with the one channel communication technology, the data storage device adopts task switching mechanisms to switch between the different command queues for execution of the operational commands queued in the different command queues.