- Patent Title: Cannabinoid receptor CB2 ligand 4-(aminomethyl)-N,N-dialkylanilines
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Application No.: US15580539Application Date: 2016-06-17
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Publication No.: US10696624B2Publication Date: 2020-06-30
- Inventor: Xiang-Qun Xie , Abdulrahman Almehizia , Peng Yang
- Applicant: UNIVERSITY OF PITTSBURGH—OF THE COMMONWEALTH SYSTEM OF HIGHER EDUCATION
- Applicant Address: US PA Pittsburgh
- Assignee: University of Pittsburgh—Of the Commonwealth System of Higher Education
- Current Assignee: University of Pittsburgh—Of the Commonwealth System of Higher Education
- Current Assignee Address: US PA Pittsburgh
- Agency: Foley & Lardner LLP
- International Application: PCT/US2016/038174 WO 20160617
- International Announcement: WO2016/205707 WO 20161222
- Main IPC: C07C311/29
- IPC: C07C311/29 ; C07D405/12 ; C07D409/12 ; C07D333/34 ; C07D333/38 ; C07C311/13 ; C07C311/18 ; C07D401/12 ; C07D241/44 ; A61P19/10 ; A61P35/00 ; C07D213/42 ; C07D317/58
Abstract:
Disclosed herein are novel cannabionid receptor-2 (CB2) agonists and inverse agonists represented by Formula (I), and method of modulating the activity of CB2 by contacting the CB-2 receptor with a compound of Formula (I). Also, disclosed are methods for treating multiple myeloma or osteoporosis in a mammal in need thereof by modulating the activity of a cannabinoid receptor-2 (CB2).
Public/Granted literature
- US20180141902A1 NOVEL CANNABINOID RECEPTOR CB2 LIGAND 4-(AMINOMETHYL)-N,N-DIALKYLANILINES Public/Granted day:2018-05-24
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