- Patent Title: Inhibitors of indoleamine 2,3-dioxygenase and methods of their use
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Application No.: US16098239Application Date: 2017-05-04
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Publication No.: US10696648B2Publication Date: 2020-06-30
- Inventor: David K. Williams , Weifang Shan , James Aaron Balog
- Applicant: BRISTOL-MYERS SQUIBB COMPANY
- Applicant Address: US NJ Princeton
- Assignee: Bristol-Myers Squibb Company
- Current Assignee: Bristol-Myers Squibb Company
- Current Assignee Address: US NJ Princeton
- Agency: BakerHostetler
- International Application: PCT/US2017/030992 WO 20170504
- International Announcement: WO2017/192811 WO 20171109
- Main IPC: C07D401/10
- IPC: C07D401/10 ; C07C275/30 ; C07C275/36 ; C07C275/34 ; C07C275/28 ; C07C275/42 ; C07C275/26 ; A61P35/00 ; A61K31/4709 ; A61K31/47 ; A61K31/277 ; A61K31/17 ; C07D401/04 ; C07D215/18 ; C07C275/32

Abstract:
There are disclosed compounds that modulate or inhibit the enzymatic activity of indoleamine 2,3-dioxygenase (IDO), pharmaceutical compositions containing said compounds and methods of treating proliferative disorders, such as cancer, viral infections and/or inflammatory disorders utilizing the compounds of the invention.
Public/Granted literature
- US20190144416A1 INHIBITORS OF INDOLEAMINE 2,3-DIOXYGENASE AND METHODS OF THEIR USE Public/Granted day:2019-05-16
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