Invention Grant
- Patent Title: Liquid bridge and system
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Application No.: US15131546Application Date: 2016-04-18
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Publication No.: US10730051B2Publication Date: 2020-08-04
- Inventor: Mark Davies , Tara Dalton , Kieran Curran
- Applicant: STOKES BIO LIMITED
- Applicant Address: IE Limerick
- Assignee: STOKES BIO LTD.
- Current Assignee: STOKES BIO LTD.
- Current Assignee Address: IE Limerick
- Agency: Jones Robb, P.L.L.C.
- Main IPC: B01L3/00
- IPC: B01L3/00 ; B01F13/00 ; B01F15/02 ; C12Q1/68 ; F17D1/08 ; C12Q1/686 ; B01L7/00

Abstract:
A bridge (30) comprises a first inlet port (31) at the end of a capillary, a narrower second inlet port (32) which is an end of a capillary, an outlet port (33) which is an end of a capillary, and a chamber (34) for silicone oil. The oil is density-matched with the reactor droplets such that a neutrally buoyant environment is created within the chamber (34). The oil within the chamber is continuously replenished by the oil separating the reactor droplets. This causes the droplets to assume a stable capillary-suspended spherical form upon entering the chamber (34). The spherical shape grows until large enough to span the gap between the ports, forming an axisymmetric liquid bridge. The introduction of a second droplet from the second inlet port (32) causes the formation of an unstable funicular bridge that quickly ruptures from the, finer, second inlet port (32), and the droplets combine at the liquid bridge (30). In another embodiment, a droplet (55) segments into smaller droplets which bridge the gap between the inlet and outlet ports.
Public/Granted literature
- US20160339435A1 Liquid Bridge and System Public/Granted day:2016-11-24
Information query
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