Invention Grant
- Patent Title: CNS targeting AAV vectors and methods of use thereof
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Application No.: US15613646Application Date: 2017-06-05
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Publication No.: US10731178B2Publication Date: 2020-08-04
- Inventor: Guangping Gao , Hongwei Zhang , Hongyan Wang , Zuoshang Xu
- Applicant: University of Massachusetts
- Applicant Address: US MA Boston
- Assignee: University of Massachusetts
- Current Assignee: University of Massachusetts
- Current Assignee Address: US MA Boston
- Agency: Wolf, Greenfield & Sacks, P.C.
- Main IPC: C12N15/86
- IPC: C12N15/86 ; A61K48/00 ; C12N15/113 ; C12N15/864 ; A61K38/50 ; A61K31/713 ; C12N9/80 ; A61P25/00 ; C12N7/00 ; C12N15/63

Abstract:
The invention in some aspects relates to recombinant adeno-associated viruses useful for targeting transgenes to CNS tissue, and compositions comprising the same, and methods of use thereof. In some aspects, the invention provides methods and compositions for treating CNS-related disorders.
Public/Granted literature
- US20180148738A9 CNS TARGETING AAV VECTORS AND METHODS OF USE THEREOF Public/Granted day:2018-05-31
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